The conformational cycle of prestin underlies outer-hair cell electromotility
The conformational cycle of prestin underlies outer-hair cell electromotility
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The voltage-dependent motor protein prestin (also known as SLC26A5) is responsible for the electromotive behaviour of outer-hair cells and underlies the cochlear amplifier
1
. Knockout or impairment of prestin causes severe hearing loss
2
–
5
. Despite the key role of prestin in hearing, the mechanism by which mammalian prestin se...
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Full title
The conformational cycle of prestin underlies outer-hair cell electromotility
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TN_cdi_proquest_miscellaneous_2586503951
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2586503951
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-04152-4