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The conformational cycle of prestin underlies outer-hair cell electromotility

The conformational cycle of prestin underlies outer-hair cell electromotility

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2586503951

The conformational cycle of prestin underlies outer-hair cell electromotility

About this item

Full title

The conformational cycle of prestin underlies outer-hair cell electromotility

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2021-12, Vol.600 (7889), p.553-558

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The voltage-dependent motor protein prestin (also known as SLC26A5) is responsible for the electromotive behaviour of outer-hair cells and underlies the cochlear amplifier
1
. Knockout or impairment of prestin causes severe hearing loss
2

5
. Despite the key role of prestin in hearing, the mechanism by which mammalian prestin se...

Alternative Titles

Full title

The conformational cycle of prestin underlies outer-hair cell electromotility

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2586503951

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2586503951

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-021-04152-4

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