Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2
About this item
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Author / Creator
Nguyen, Linh , McCord, Kelli A. , Bui, Duong T. , Bouwman, Kim M. , Kitova, Elena N. , Elaish, Mohamed , Kumawat, Dhanraj , Daskhan, Gour C. , Tomris, Ilhan , Han, Ling , Chopra, Pradeep , Yang, Tzu-Jing , Willows, Steven D. , Mason, Andrew L. , Mahal, Lara K. , Lowary, Todd L. , West, Lori J. , Hsu, Shang-Te Danny , Hobman, Tom , Tompkins, Stephen M. , Boons, Geert-Jan , de Vries, Robert P. , Macauley, Matthew S. and Klassen, John S.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Emerging evidence suggests that host glycans influence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we reveal that the receptor-binding domain (RBD) of the spike (S) protein on SARS-CoV-2 recognizes oligosaccharides containing sialic acid (Sia), with preference for monosialylated gangliosides. Gangliosides embedded...
Alternative Titles
Full title
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2
Authors, Artists and Contributors
Author / Creator
McCord, Kelli A.
Bui, Duong T.
Bouwman, Kim M.
Kitova, Elena N.
Elaish, Mohamed
Kumawat, Dhanraj
Daskhan, Gour C.
Tomris, Ilhan
Han, Ling
Chopra, Pradeep
Yang, Tzu-Jing
Willows, Steven D.
Mason, Andrew L.
Mahal, Lara K.
Lowary, Todd L.
West, Lori J.
Hsu, Shang-Te Danny
Hobman, Tom
Tompkins, Stephen M.
Boons, Geert-Jan
de Vries, Robert P.
Macauley, Matthew S.
Klassen, John S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2596014898
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2596014898
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-021-00924-1
