Structural basis for the tethered peptide activation of adhesion GPCRs
Structural basis for the tethered peptide activation of adhesion GPCRs
About this item
Full title
Author / Creator
Ping, Yu-Qi , Xiao, Peng , Yang, Fan , Zhao, Ru-Jia , Guo, Sheng-Chao , Yan, Xu , Wu, Xiang , Zhang, Chao , Lu, Yan , Zhao, Fenghui , Zhou, Fulai , Xi, Yue-Tong , Yin, Wanchao , Liu, Feng-Zhen , He, Dong-Fang , Zhang, Dao-Lai , Zhu, Zhong-Liang , Jiang, Yi , Du, Lutao , Feng, Shi-Qing , Schöneberg, Torsten , Liebscher, Ines , Xu, H. Eric and Sun, Jin-Peng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Adhesion G-protein-coupled receptors (aGPCRs) are important for organogenesis, neurodevelopment, reproduction and other processes
1
–
6
. Many aGPCRs are activated by a conserved internal (tethered) agonist sequence known as the Stachel sequence
7
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12
. Here, we report the cryogenic electron microscopy (cryo-EM) structures...
Alternative Titles
Full title
Structural basis for the tethered peptide activation of adhesion GPCRs
Authors, Artists and Contributors
Author / Creator
Xiao, Peng
Yang, Fan
Zhao, Ru-Jia
Guo, Sheng-Chao
Yan, Xu
Wu, Xiang
Zhang, Chao
Lu, Yan
Zhao, Fenghui
Zhou, Fulai
Xi, Yue-Tong
Yin, Wanchao
Liu, Feng-Zhen
He, Dong-Fang
Zhang, Dao-Lai
Zhu, Zhong-Liang
Jiang, Yi
Du, Lutao
Feng, Shi-Qing
Schöneberg, Torsten
Liebscher, Ines
Xu, H. Eric
Sun, Jin-Peng
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2650252001
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2650252001
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04619-y
