Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory...
Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory follicular lymphoma: a single-arm, multicentre, phase 2 study
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Author / Creator
Budde, Lihua E, MD , Sehn, Laurie H , Matasar, Matthew, MD , Schuster, Stephen J, MD , Assouline, Sarit, MD , Giri, Pratyush, MBBS , Kuruvilla, John, MD , Canales, Miguel, MD , Dietrich, Sascha, MD , Fay, Keith, MBChB , Ku, Matthew, MBBS , Nastoupil, Loretta, MD , Cheah, Chan Yoon, MBBS , Wei, Michael C, MD , Yin, Shen, PhD , Li, Chi-Chung, PhD , Huang, Huang, MSc , Kwan, Antonia, MBBS , Penuel, Elicia, PhD and Bartlett, Nancy L, Prof
Publisher
London: Elsevier Ltd
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Language
English
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Publisher
London: Elsevier Ltd
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Contents
SummaryBackgroundMosunetuzumab is a CD20 × CD3 T-cell-engaging bispecific monoclonal antibody that redirects T cells to eliminate malignant B cells. In a phase 1 study, mosunetuzumab was well tolerated and active in patients with relapsed or refractory B-cell lymphoma. We, therefore, aimed to evaluate the safety and anti-tumour activity of fixed-du...
Alternative Titles
Full title
Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory follicular lymphoma: a single-arm, multicentre, phase 2 study
Authors, Artists and Contributors
Author / Creator
Sehn, Laurie H
Matasar, Matthew, MD
Schuster, Stephen J, MD
Assouline, Sarit, MD
Giri, Pratyush, MBBS
Kuruvilla, John, MD
Canales, Miguel, MD
Dietrich, Sascha, MD
Fay, Keith, MBChB
Ku, Matthew, MBBS
Nastoupil, Loretta, MD
Cheah, Chan Yoon, MBBS
Wei, Michael C, MD
Yin, Shen, PhD
Li, Chi-Chung, PhD
Huang, Huang, MSc
Kwan, Antonia, MBBS
Penuel, Elicia, PhD
Bartlett, Nancy L, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2687722824
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2687722824
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(22)00335-7