Conserved class B GPCR activation by a biased intracellular agonist
Conserved class B GPCR activation by a biased intracellular agonist
About this item
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Author / Creator
Zhao, Li-Hua , He, Qian , Yuan, Qingning , Gu, Yimin , He, Xinheng , Shan, Hong , Li, Junrui , Wang, Kai , Li, Yang , Hu, Wen , Wu, Kai , Shen, Jianhua and Xu, H. Eric
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Class B G-protein-coupled receptors (GPCRs), including glucagon-like peptide 1 receptor (GLP1R) and parathyroid hormone 1 receptor (PTH1R), are important drug targets
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–
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. Injectable peptide drugs targeting these receptors have been developed, but orally available small-molecule drugs remain under development
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. Here...
Alternative Titles
Full title
Conserved class B GPCR activation by a biased intracellular agonist
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Record Identifier
TN_cdi_proquest_miscellaneous_2844679583
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2844679583
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06467-w
