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Structural insights into cytokine cleavage by inflammatory caspase-4

Structural insights into cytokine cleavage by inflammatory caspase-4

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2892946494

Structural insights into cytokine cleavage by inflammatory caspase-4

About this item

Full title

Structural insights into cytokine cleavage by inflammatory caspase-4

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-12, Vol.624 (7991), p.451-459

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inflammatory caspases are key enzymes in mammalian innate immunity that control the processing and release of interleukin-1 (IL-1)-family cytokines
1
,
2
. Despite the biological importance, the structural basis for inflammatory caspase-mediated cytokine processing has remained unclear. To date, catalytic cleavage of IL-1-family members...

Alternative Titles

Full title

Structural insights into cytokine cleavage by inflammatory caspase-4

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2892946494

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2892946494

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06751-9

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