RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammat...
RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies
About this item
Full title
Author / Creator
Publisher
England: National Library of Medicine - MEDLINE Abstracts
Journal title
Language
English
Formats
Publication information
Publisher
England: National Library of Medicine - MEDLINE Abstracts
Subjects
More information
Scope and Contents
Contents
Rat adjuvant-induced arthritis (AIA) and collagen-induced arthritis (CIA) feature bone loss and systemic increases in TNFalpha, IL-1beta, and receptor activator of NF-kappaB ligand (RANKL). Anti-IL-1 or anti-TNFalpha therapies consistently reduce inflammation in these models, but systemic bone loss often persists. RANKL inhibition consistently prev...
Alternative Titles
Full title
RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_733543943
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733543943
Other Identifiers
ISSN
1478-6354
E-ISSN
1478-6362
DOI
10.1186/ar2879
