Simultaneous alignment of short reads against multiple genomes
Simultaneous alignment of short reads against multiple genomes
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Genome resequencing with short reads generally relies on alignments against a single reference. GenomeMapper supports simultaneous mapping of short reads against multiple genomes by integrating related genomes (e.g., individuals of the same species) into a single graph structure. It constitutes the first approach for handling multiple references and introduces representations for alignments against complex structures. Demonstrated benefits include access to polymorphisms that cannot be identified by alignments against the reference alone. Download GenomeMapper at http://1001genomes.org....
Alternative Titles
Full title
Simultaneous alignment of short reads against multiple genomes
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Record Identifier
TN_cdi_proquest_miscellaneous_734113323
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734113323
Other Identifiers
ISSN
1474-760X
E-ISSN
1474-760X
DOI
10.1186/gb-2009-10-9-r98
