Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In mammalian cells, Id proteins coordinate proliferation and differentiation. Id2 is a dominant-negative antagonist of basic helix–loop–helix transcription factors and proteins of the retinoblastoma (Rb) family. Here we show that
Id2
–
Rb
double knockout embryos survive to term with minimal or no defects in neurogenesis and haematopoies...
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Full title
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
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TN_cdi_proquest_miscellaneous_743158835
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743158835
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/35036504
