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Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_761043316

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

About this item

Full title

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (43), p.18569-18574

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Damaging interactions between antibodies and brain antigenic targets may be responsible for an expanding range of neurological disorders. In the case of systemic lupus erythematosus (SLE), patients generate autoantibodies (AAbs) that frequently bind dsDNA. Although some symptoms of SLE may arise from direct reactivity to dsDNA, much of the AAb-medi...

Alternative Titles

Full title

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_761043316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_761043316

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1006980107

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