HLA-A3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans
HLA-A3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans
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Author / Creator
McCormack, Mark , Alfirevic, Ana , Bourgeois, Stephane , Farrell, John J , Kasperavičiūtė, Dalia , Carrington, Mary , Sills, Graeme J , Marson, Tony , Jia, Xiaoming , de Bakker, Paul I.W , Chinthapalli, Krishna , Molokhia, Mariam , Johnson, Michael R , O'Connor, Gerard D , Chaila, Elijah , Alhusaini, Saud , Shianna, Kevin V , Radtke, Rodney A , Heinzen, Erin L , Walley, Nicole , Pandolfo, Massimo , Pichler, Werner , Park, B. Kevin , Depondt, Chantal , Sisodiya, Sanjay M , Goldstein, David B , Deloukas, Panos , Delanty, Norman , Cavalleri, Gianpiero L and Pirmohamed, Munir
Publisher
Waltham, MA: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Waltham, MA: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
A strong association between the HLA-B*1502 allele and SJS and TEN induced by carbamazepine has been shown. This study involving Europeans implicates a different HLA allele, HLA-A*3101, in conferring susceptibility to a broad range of carbamazepine-induced reactions.
Carbamazepine is one of the most commonly prescribed drugs for the treatment of...
Alternative Titles
Full title
HLA-A3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans
Authors, Artists and Contributors
Author / Creator
Alfirevic, Ana
Bourgeois, Stephane
Farrell, John J
Kasperavičiūtė, Dalia
Carrington, Mary
Sills, Graeme J
Marson, Tony
Jia, Xiaoming
de Bakker, Paul I.W
Chinthapalli, Krishna
Molokhia, Mariam
Johnson, Michael R
O'Connor, Gerard D
Chaila, Elijah
Alhusaini, Saud
Shianna, Kevin V
Radtke, Rodney A
Heinzen, Erin L
Walley, Nicole
Pandolfo, Massimo
Pichler, Werner
Park, B. Kevin
Depondt, Chantal
Sisodiya, Sanjay M
Goldstein, David B
Deloukas, Panos
Delanty, Norman
Cavalleri, Gianpiero L
Pirmohamed, Munir
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_858776673
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_858776673
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1013297
