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Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activ...

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_876813130

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

About this item

Full title

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (28), p.11332-11337

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Protein glycosylation is an important posttranslational process, which regulates protein folding and functional expression. Studies have shown that abnormal glycosylation in tumor cells affects cancer progression and malignancy. In the current study, we have identified sialylated proteins using an alkynyl sugar probe in two different lung cancer ce...

Alternative Titles

Full title

Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_876813130

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_876813130

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1107385108

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