RANK Is the Intrinsic Hematopoietic Cell Surface Receptor That Controls Osteoclastogenesis and Regul...
RANK Is the Intrinsic Hematopoietic Cell Surface Receptor That Controls Osteoclastogenesis and Regulation of Bone Mass and Calcium Metabolism
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Author / Creator
Li, Ji , Sarosi, Ildiko , Yan, Xiao-Qiang , Morony, Sean , Capparelli, Casey , Tan, Hong-Lin , McCabe, Susan , Elliott, Robin , Scully, Sheila , Van, Gwyneth , Kaufman, Stephen , Juan, Shao-Chieh , Sun, Yu , Tarpley, John , Martin, Laura , Christensen, Kathleen , McCabe, James , Kostenuik, Paul , Hsu, Hailing , Fletcher, Frederick , Dunstan, Colin R. , Lacey, David L. and Boyle, William J.
Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences of the United States of America
Subjects
More information
Scope and Contents
Contents
We have generated RANK (receptor activator of NF-κ B nullizygous mice to determine the molecular genetic interactions between osteoprotegerin, osteoprotegerin ligand, and RANK during bone resorption and remodeling processes. RANK-/-mice lack osteoclasts and have a profound defect in bone resorption and remodeling and in the development of the carti...
Alternative Titles
Full title
RANK Is the Intrinsic Hematopoietic Cell Surface Receptor That Controls Osteoclastogenesis and Regulation of Bone Mass and Calcium Metabolism
Authors, Artists and Contributors
Author / Creator
Sarosi, Ildiko
Yan, Xiao-Qiang
Morony, Sean
Capparelli, Casey
Tan, Hong-Lin
McCabe, Susan
Elliott, Robin
Scully, Sheila
Van, Gwyneth
Kaufman, Stephen
Juan, Shao-Chieh
Sun, Yu
Tarpley, John
Martin, Laura
Christensen, Kathleen
McCabe, James
Kostenuik, Paul
Hsu, Hailing
Fletcher, Frederick
Dunstan, Colin R.
Lacey, David L.
Boyle, William J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_10677500
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10677500
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.97.4.1566