Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obs...
Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obstacle of HBV cure
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Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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Language
English
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Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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Scope and Contents
Contents
ObjectivesA major goal of curative hepatitis B virus (HBV) treatments is the reduction or inactivation of intrahepatic viral covalently closed circular DNA (cccDNA). Hence, precise cccDNA quantification is essential in preclinical and clinical studies. Southern blot (SB) permits cccDNA visualisation but lacks sensitivity and is very laborious. Quan...
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Full title
Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obstacle of HBV cure
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10086470
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10086470
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2022-328380
