Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems
About this item
Full title
Author / Creator
Wu, Han , Liu, Qishuai , Shi, Hui , Xie, Jingke , Zhang, Quanjun , Ouyang, Zhen , Li, Nan , Yang, Yi , Liu, Zhaoming , Zhao, Yu , Lai, Chengdan , Ruan, Degong , Peng, Jiangyun , Ge, Weikai , Chen, Fangbing , Fan, Nana , Jin, Qin , Liang, Yanhui , Lan, Ting , Yang, Xiaoyu , Wang, Xiaoshan , Lei, Zhiyong , Doevendans, Pieter A. , Sluijter, Joost P. G. , Wang, Kepin , Li, Xiaoping and Lai, Liangxue
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
CRISPR
/
Cpf1 features a number of properties that are distinct from CRISPR
/
Cas9 and provides an excellent alternative to Cas9 for genome editing. To date, genome engineering by CRISPR
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Cpf1 has been reported only in human cells and mouse embryos of mammalian systems and its efficiency is ultimately lower than that of Cas9 prot...
Alternative Titles
Full title
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems
Authors, Artists and Contributors
Author / Creator
Liu, Qishuai
Shi, Hui
Xie, Jingke
Zhang, Quanjun
Ouyang, Zhen
Li, Nan
Yang, Yi
Liu, Zhaoming
Zhao, Yu
Lai, Chengdan
Ruan, Degong
Peng, Jiangyun
Ge, Weikai
Chen, Fangbing
Fan, Nana
Jin, Qin
Liang, Yanhui
Lan, Ting
Yang, Xiaoyu
Wang, Xiaoshan
Lei, Zhiyong
Doevendans, Pieter A.
Sluijter, Joost P. G.
Wang, Kepin
Li, Xiaoping
Lai, Liangxue
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105780
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105780
Other Identifiers
ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-018-2810-3
