Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates...
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
About this item
Full title
Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
The two iron regulatory proteins IRP1 and IRP2 bind to transcripts of ferritin, transferrin receptor and other target genes to control the expression of iron metabolism proteins at the post‐transcriptional level. Here we compare the effects of genetic ablation of IRP1 to IRP2 in mice. IRP1−/− mice misregulate iron metabolism only in the kidney and...
Alternative Titles
Full title
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1271751
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1271751
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/sj.emboj.7600041
