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Substrate selection by the proteasome during degradation of protein complexes

Substrate selection by the proteasome during degradation of protein complexes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2670781

Substrate selection by the proteasome during degradation of protein complexes

About this item

Full title

Substrate selection by the proteasome during degradation of protein complexes

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2009-01, Vol.5 (1), p.29-36

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The proteasome controls the turnover of many cellular proteins. Two structural features are typically required for proteins to be degraded: covalently attached ubiquitin polypeptides that allow binding to the proteasome and an unstructured region in the targeted protein that initiates proteolysis. Here, we have tested the degradation of model prote...

Alternative Titles

Full title

Substrate selection by the proteasome during degradation of protein complexes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2670781

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2670781

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.130

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