Substrate selection by the proteasome during degradation of protein complexes
Substrate selection by the proteasome during degradation of protein complexes
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The proteasome controls the turnover of many cellular proteins. Two structural features are typically required for proteins to be degraded: covalently attached ubiquitin polypeptides that allow binding to the proteasome and an unstructured region in the targeted protein that initiates proteolysis. Here, we have tested the degradation of model prote...
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Full title
Substrate selection by the proteasome during degradation of protein complexes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2670781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2670781
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.130