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A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_291814

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

About this item

Full title

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2003-12, Vol.22 (24), p.6494-6504

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

ARC92/ACID1 was identified as a novel specific target of the herpes simplex transactivator VP16 using an affinity purification procedure. Characterization of the protein revealed tight interactions with human Mediator mediated through a von Willebrand type A domain. ARC92/ACID1 further contains a novel activator‐interacting domain (ACID), which it...

Alternative Titles

Full title

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_291814

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_291814

Other Identifiers

ISSN

0261-4189,1460-2075

E-ISSN

1460-2075

DOI

10.1093/emboj/cdg619

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