A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
ARC92/ACID1 was identified as a novel specific target of the herpes simplex transactivator VP16 using an affinity purification procedure. Characterization of the protein revealed tight interactions with human Mediator mediated through a von Willebrand type A domain. ARC92/ACID1 further contains a novel activator‐interacting domain (ACID), which it...
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Full title
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_291814
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_291814
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ISSN
0261-4189,1460-2075
E-ISSN
1460-2075
DOI
10.1093/emboj/cdg619