Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Homologous recombination maintains genomic stability in mammalian mitotic cells through precise templated repair of DNA double-strand breaks and other lesions. The outcome of homologous recombination is typically precise when the sister chromatid is the donor template.
Homologous recombination is a coordinated process involving the...
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Full title
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3261768
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3261768
Other Identifiers
ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm2851
