Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
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Full title
Author / Creator
Meister, Stephan , Plouffe, David M. , Kuhen, Kelli L. , Bonamy, Ghislain M. C. , Wu, Tao , Barnes, S. Whitney , Bopp, Selina E. , Borboa, Rachel , Bright, A. Taylor , Che, Jianwei , Cohen, Steve , Dharia, Neekesh V. , Gagaring, Kerstin , Gettayacamin, Montip , Gordon, Perry , Groessl, Todd , Kato, Nobutaka , Lee, Marcus C. S. , McNamara, Case W. , Fidock, David A. , Nagle, Advait , Nam, Tae-gyu , Richmond, Wendy , Roland, Jason , Rottmann, Matthias , Zhou, Bin , Froissard, Patrick , Glynne, Richard J. , Mazier, Dominique , Sattabongkot, Jetsumon , Schultz, Peter G. , Tuntland, Tove , Walker, John R. , Zhou, Yingyao , Chatterjee, Arnab , Diagana, Thierry T. and Winzeler, Elizabeth A.
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against both erythrocytic and exo-erythrocytic forms would be preferable. We applied a multifactorial approach to a set of > 4000 commercially available compounds with previously demonstrated blood-...
Alternative Titles
Full title
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
Authors, Artists and Contributors
Author / Creator
Plouffe, David M.
Kuhen, Kelli L.
Bonamy, Ghislain M. C.
Wu, Tao
Barnes, S. Whitney
Bopp, Selina E.
Borboa, Rachel
Bright, A. Taylor
Che, Jianwei
Cohen, Steve
Dharia, Neekesh V.
Gagaring, Kerstin
Gettayacamin, Montip
Gordon, Perry
Groessl, Todd
Kato, Nobutaka
Lee, Marcus C. S.
McNamara, Case W.
Fidock, David A.
Nagle, Advait
Nam, Tae-gyu
Richmond, Wendy
Roland, Jason
Rottmann, Matthias
Zhou, Bin
Froissard, Patrick
Glynne, Richard J.
Mazier, Dominique
Sattabongkot, Jetsumon
Schultz, Peter G.
Tuntland, Tove
Walker, John R.
Zhou, Yingyao
Chatterjee, Arnab
Diagana, Thierry T.
Winzeler, Elizabeth A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3473092
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3473092
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1211936
