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A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium

A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3527005

A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium

About this item

Full title

A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2012-08, Vol.337 (6098), p.1091-1093

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Diseases of the esophageal epithelium (EE), such as reflux esophagitis and cancer, are rising in incidence. Despite this, the cellular behaviors underlying EE homeostasis and repair remain controversial. Here, we show that in mice, EE is maintained by a single population of cells that divide stochastically to generate proliferating and differentiat...

Alternative Titles

Full title

A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3527005

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3527005

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1218835

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