Mitonuclear protein imbalance as a conserved longevity mechanism
Mitonuclear protein imbalance as a conserved longevity mechanism
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Longevity is regulated by a network of closely linked metabolic systems. We used a combination of mouse population genetics and RNA interference in
Caenorhabditis elegans
to identify mitochondrial ribosomal protein S5 (
Mrps5
) and other mitochondrial ribosomal proteins as metabolic and longevity regulators. MRP knockdown triggers miton...
Alternative Titles
Full title
Mitonuclear protein imbalance as a conserved longevity mechanism
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3663447
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3663447
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12188
