KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling
About this item
Full title
Author / Creator
Wagner, Klaus W , Alam, Hunain , Dhar, Shilpa S , Giri, Uma , Li, Na , Wei, Yongkun , Giri, Dipak , Cascone, Tina , Kim, Jae-Hwan , Ye, Yuanqing , Multani, Asha S , Chan, Chia-Hsin , Erez, Baruch , Saigal, Babita , Chung, Jimyung , Lin, Hui-Kuan , Wu, Xifeng , Hung, Mien-Chie , Heymach, John V and Lee, Min Gyu
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Epigenetic dysregulation has emerged as a major contributor to tumorigenesis. Histone methylation is a well-established mechanism of epigenetic regulation that is dynamically modulated by histone methyltransferases and demethylases. The pathogenic role of histone methylation modifiers in non-small cell lung cancer (NSCLC), which is the leading caus...
Alternative Titles
Full title
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859406
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859406
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI68642
