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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3927413

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

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Publication information

Publisher

London: Nature Publishing Group UK

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Scope and Contents

Contents

Molecular alterations in
KRAS
are associated with acquired resistance to anti-epidermal growth factor receptor (EGFR) treatment in colorectal cancer; resistant mutations can be identified in the blood of patients, months before clinical evidence of disease progression.
Acquired resistance in anti-EGFR therapy
Antibodies targeting epider...

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Full title

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3927413

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3927413

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature11156

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