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Trastuzumab emtansine: mechanisms of action and drug resistance

Trastuzumab emtansine: mechanisms of action and drug resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4058749

Trastuzumab emtansine: mechanisms of action and drug resistance

About this item

Full title

Trastuzumab emtansine: mechanisms of action and drug resistance

Publisher

England: BioMed Central Ltd

Journal title

Breast cancer research : BCR, 2014-03, Vol.16 (2), p.209-R22, Article 209

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Trastuzumab emtansine (T-DM1) is an antibody-drug conjugate that is effective and generally well tolerated when administered as a single agent to treat advanced breast cancer. Efficacy has now been demonstrated in randomized trials as first line, second line, and later than the second line treatment of advanced breast cancer. T-DM1 is currently bei...

Alternative Titles

Full title

Trastuzumab emtansine: mechanisms of action and drug resistance

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4058749

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4058749

Other Identifiers

ISSN

1465-542X,1465-5411

E-ISSN

1465-542X

DOI

10.1186/bcr3621

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