All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins
About this item
Full title
Author / Creator
Hochbaum, Daniel R , Zhao, Yongxin , Farhi, Samouil L , Klapoetke, Nathan , Werley, Christopher A , Kapoor, Vikrant , Zou, Peng , Kralj, Joel M , Maclaurin, Dougal , Smedemark-Margulies, Niklas , Saulnier, Jessica L , Boulting, Gabriella L , Straub, Christoph , Cho, Yong Ku , Melkonian, Michael , Wong, Gane Ka-Shu , Harrison, D Jed , Murthy, Venkatesh N , Sabatini, Bernardo L , Boyden, Edward S , Campbell, Robert E and Cohen, Adam E
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
A combination of a sensitive blue light–gated channelrhodopsin actuator and red-shifted Arch-based voltage sensors allows all-optical electrophysiology without cross-talk in cultured neurons or brain slices.
All-optical electrophysiology—spatially resolved simultaneous optical perturbation and measurement of membrane voltage—would open new vista...
Alternative Titles
Full title
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins
Authors, Artists and Contributors
Author / Creator
Zhao, Yongxin
Farhi, Samouil L
Klapoetke, Nathan
Werley, Christopher A
Kapoor, Vikrant
Zou, Peng
Kralj, Joel M
Maclaurin, Dougal
Smedemark-Margulies, Niklas
Saulnier, Jessica L
Boulting, Gabriella L
Straub, Christoph
Cho, Yong Ku
Melkonian, Michael
Wong, Gane Ka-Shu
Harrison, D Jed
Murthy, Venkatesh N
Sabatini, Bernardo L
Boyden, Edward S
Campbell, Robert E
Cohen, Adam E
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4117813
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4117813
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.3000
