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DC isoketal-modified proteins activate T cells and promote hypertension

DC isoketal-modified proteins activate T cells and promote hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4220659

DC isoketal-modified proteins activate T cells and promote hypertension

About this item

Full title

DC isoketal-modified proteins activate T cells and promote hypertension

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-10, Vol.124 (10), p.4642-4656

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Oxidative damage and inflammation are both implicated in the genesis of hypertension; however, the mechanisms by which these stimuli promote hypertension are not fully understood. Here, we have described a pathway in which hypertensive stimuli promote dendritic cell (DC) activation of T cells, ultimately leading to hypertension. Using multiple muri...

Alternative Titles

Full title

DC isoketal-modified proteins activate T cells and promote hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4220659

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4220659

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI74084

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