Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay
Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
ABHD16A is identified as a major enzyme catalyzing production of lyso-PS from phosphatidylserine (PS). A new ABHD16A inhibitor and knockout mice show a dynamic interplay occurring during inflammation between ABHD16A and disease-linked ABHD12, an enzyme that degrades lyso-PS.
ABHD16A is identified as a major enzyme catalyzing production of lyso-P...
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Full title
Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301979
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301979
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.1721