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Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301979

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

About this item

Full title

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2015-02, Vol.11 (2), p.164-171

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

ABHD16A is identified as a major enzyme catalyzing production of lyso-PS from phosphatidylserine (PS). A new ABHD16A inhibitor and knockout mice show a dynamic interplay occurring during inflammation between ABHD16A and disease-linked ABHD12, an enzyme that degrades lyso-PS.
ABHD16A is identified as a major enzyme catalyzing production of lyso-P...

Alternative Titles

Full title

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301979

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301979

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.1721

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