RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
About this item
Full title
Author / Creator
Niederst, Matthew J. , Sequist, Lecia V. , Poirier, John T. , Mermel, Craig H. , Lockerman, Elizabeth L. , Garcia, Angel R. , Katayama, Ryohei , Costa, Carlotta , Ross, Kenneth N. , Moran, Teresa , Howe, Emily , Fulton, Linnea E. , Mulvey, Hillary E. , Bernardo, Lindsay A. , Mohamoud, Farhiya , Miyoshi, Norikatsu , VanderLaan, Paul A. , Costa, Daniel B. , Jänne, Pasi A. , Borger, Darrell R. , Ramaswamy, Sridhar , Shioda, Toshi , Iafrate, Anthony J. , Getz, Gad , Rudin, Charles M. , Mino-Kenudson, Mari and Engelman, Jeffrey A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Tyrosine kinase inhibitors are effective treatments for non-small-cell lung cancers (NSCLCs) with
epidermal growth factor receptor
(
EGFR
) mutations. However, relapse typically occurs after an average of 1 year of continuous treatment. A fundamental histological transformation from NSCLC to small-cell lung cancer (SCLC) is observed in...
Alternative Titles
Full title
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
Authors, Artists and Contributors
Author / Creator
Sequist, Lecia V.
Poirier, John T.
Mermel, Craig H.
Lockerman, Elizabeth L.
Garcia, Angel R.
Katayama, Ryohei
Costa, Carlotta
Ross, Kenneth N.
Moran, Teresa
Howe, Emily
Fulton, Linnea E.
Mulvey, Hillary E.
Bernardo, Lindsay A.
Mohamoud, Farhiya
Miyoshi, Norikatsu
VanderLaan, Paul A.
Costa, Daniel B.
Jänne, Pasi A.
Borger, Darrell R.
Ramaswamy, Sridhar
Shioda, Toshi
Iafrate, Anthony J.
Getz, Gad
Rudin, Charles M.
Mino-Kenudson, Mari
Engelman, Jeffrey A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4357281
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4357281
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7377
