Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia
Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia
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Author / Creator
Dorrance, A M , Neviani, P , Ferenchak, G J , Huang, X , Nicolet, D , Maharry, K S , Ozer, H G , Hoellarbauer, P , Khalife, J , Hill, E B , Yadav, M , Bolon, B N , Lee, R J , Lee, L J , Croce, C M , Garzon, R , Caligiuri, M A , Bloomfield, C D and Marcucci, G
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Current treatments for acute myeloid leukemia (AML) are designed to target rapidly dividing blast populations with limited success in eradicating the functionally distinct leukemia stem cell (LSC) population, which is postulated to be responsible for disease resistance and relapse. We have previously reported high miR-126 expression levels to be as...
Alternative Titles
Full title
Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4633325
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4633325
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2015.139
