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Complex interactions between the DNA-damage response and mammalian telomeres

Complex interactions between the DNA-damage response and mammalian telomeres

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4739752

Complex interactions between the DNA-damage response and mammalian telomeres

About this item

Full title

Complex interactions between the DNA-damage response and mammalian telomeres

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2015-11, Vol.22 (11), p.859-866

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The shelterin complex sequesters the linear ends of chromosomes and prevents telomeres from being recognized as DNA double-strand breaks. In this Review, the authors discuss the complex interactions between shelterin components and DNA damage–response factors and consider shelterin's emerging roles as regulators of genome integrity and cell fate.

Alternative Titles

Full title

Complex interactions between the DNA-damage response and mammalian telomeres

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4739752

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4739752

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.3092

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