Complex interactions between the DNA-damage response and mammalian telomeres
Complex interactions between the DNA-damage response and mammalian telomeres
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Scope and Contents
Contents
The shelterin complex sequesters the linear ends of chromosomes and prevents telomeres from being recognized as DNA double-strand breaks. In this Review, the authors discuss the complex interactions between shelterin components and DNA damage–response factors and consider shelterin's emerging roles as regulators of genome integrity and cell fate.
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Complex interactions between the DNA-damage response and mammalian telomeres
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4739752
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4739752
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3092