Sirtuins as regulators of metabolism and healthspan
Sirtuins as regulators of metabolism and healthspan
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
Sirtuins regulate protein function by NAD
+
-dependent post-translational modification, thereby representing a metabolic sensor.
Compounds activating sirtuins could be used to treat age-associated mitochondrial diseases.
Activation of SIRT1 improves metabolism and global health in organisms ranging from
Caenorhabditis e...
Alternative Titles
Full title
Sirtuins as regulators of metabolism and healthspan
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872805
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872805
Other Identifiers
ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm3293