Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
About this item
Full title
Author / Creator
Hyman, David M , Puzanov, Igor , Subbiah, Vivek , Faris, Jason E , Chau, Ian , Blay, Jean-Yves , Wolf, Jürgen , Raje, Noopur S , Diamond, Eli L , Hollebecque, Antoine , Gervais, Radj , Elez-Fernandez, Maria Elena , Italiano, Antoine , Hofheinz, Ralf-Dieter , Hidalgo, Manuel , Chan, Emily , Schuler, Martin , Lasserre, Susan Frances , Makrutzki, Martina , Sirzen, Florin , Veronese, Maria Luisa , Tabernero, Josep and Baselga, José
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a basket trial that included patients with a variety of cancers, all of which contained a
BRAF
V600 mutation, the rate of response to vemurafenib was highly variable. The histologic context influences the response to BRAF inhibition.
BRAF
V600 mutations occur in approximately 50% of cutaneous melanomas and result in constitutive acti...
Alternative Titles
Full title
Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
Authors, Artists and Contributors
Author / Creator
Puzanov, Igor
Subbiah, Vivek
Faris, Jason E
Chau, Ian
Blay, Jean-Yves
Wolf, Jürgen
Raje, Noopur S
Diamond, Eli L
Hollebecque, Antoine
Gervais, Radj
Elez-Fernandez, Maria Elena
Italiano, Antoine
Hofheinz, Ralf-Dieter
Hidalgo, Manuel
Chan, Emily
Schuler, Martin
Lasserre, Susan Frances
Makrutzki, Martina
Sirzen, Florin
Veronese, Maria Luisa
Tabernero, Josep
Baselga, José
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4971773
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4971773
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1502309
