Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Pancreatic adenocarcinoma cells drive autophagy in tumour microenvironment-associated stellate cells, which release alanine that is used by the cancer cells as a carbon source for a variety of metabolic processes in an otherwise nutrient-poor environment.
A cancer cell support network dissected
Cancer cells generally have metabolic needs that...
Alternative Titles
Full title
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5228623
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5228623
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature19084