Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antivir...
Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects
About this item
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Author / Creator
Bekerman, Elena , Neveu, Gregory , Shulla, Ana , Brannan, Jennifer , Pu, Szu-Yuan , Wang, Stanley , Xiao, Fei , Barouch-Bentov, Rina , Bakken, Russell R. , Mateo, Roberto , Govero, Jennifer , Nagamine, Claude M. , Diamond, Michael S. , De Jonghe, Steven , Herdewijn, Piet , Dye, John M. , Randall, Glenn and Einav, Shirit
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Global health is threatened by emerging viral infections, which largely lack effective vaccines or therapies. Targeting host pathways that are exploited by multiple viruses could offer broad-spectrum solutions. We previously reported that AAK1 and GAK, kinase regulators of the host adaptor proteins AP1 and AP2, are essential for hepatitis C virus (...
Alternative Titles
Full title
Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5373883
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5373883
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI89857
