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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 pa...

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 pa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5461196

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

About this item

Full title

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Author / Creator

Zehir, Ahmet , Benayed, Ryma , Shah, Ronak H , Syed, Aijazuddin , Middha, Sumit , Kim, Hyunjae R , Srinivasan, Preethi , Gao, Jianjiong , Chakravarty, Debyani , Devlin, Sean M , Hellmann, Matthew D , Barron, David A , Schram, Alison M , Hameed, Meera , Dogan, Snjezana , Ross, Dara S , Hechtman, Jaclyn F , DeLair, Deborah F , Yao, JinJuan , Mandelker, Diana L , Cheng, Donavan T , Chandramohan, Raghu , Mohanty, Abhinita S , Ptashkin, Ryan N , Jayakumaran, Gowtham , Prasad, Meera , Syed, Mustafa H , Rema, Anoop Balakrishnan , Liu, Zhen Y , Nafa, Khedoudja , Borsu, Laetitia , Sadowska, Justyna , Casanova, Jacklyn , Bacares, Ruben , Kiecka, Iwona J , Razumova, Anna , Son, Julie B , Stewart, Lisa , Baldi, Tessara , Mullaney, Kerry A , Al-Ahmadie, Hikmat , Vakiani, Efsevia , Abeshouse, Adam A , Penson, Alexander V , Jonsson, Philip , Camacho, Niedzica , Chang, Matthew T , Won, Helen H , Gross, Benjamin E , Kundra, Ritika , Heins, Zachary J , Chen, Hsiao-Wei , Phillips, Sarah , Zhang, Hongxin , Wang, Jiaojiao , Ochoa, Angelica , Wills, Jonathan , Eubank, Michael , Thomas, Stacy B , Gardos, Stuart M , Reales, Dalicia N , Galle, Jesse , Durany, Robert , Cambria, Roy , Abida, Wassim , Cercek, Andrea , Feldman, Darren R , Gounder, Mrinal M , Hakimi, A Ari , Harding, James J , Iyer, Gopa , Janjigian, Yelena Y , Jordan, Emmet J , Kelly, Ciara M , Lowery, Maeve A , Morris, Luc G T , Omuro, Antonio M , Raj, Nitya , Razavi, Pedram , Shoushtari, Alexander N , Shukla, Neerav , Soumerai, Tara E , Varghese, Anna M , Yaeger, Rona , Coleman, Jonathan , Bochner, Bernard , Riely, Gregory J , Saltz, Leonard B , Scher, Howard I , Sabbatini, Paul J , Robson, Mark E , Klimstra, David S , Taylor, Barry S , Baselga, Jose , Schultz, Nikolaus , Hyman, David M , Arcila, Maria E , Solit, David B , Ladanyi, Marc and Berger, Michael F

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2017-06, Vol.23 (6), p.703-713

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

MSK-IMPACT is a clinical sequencing platform able to detect genomic mutations, copy number alterations and structural variants in a panel of cancer-related genes. This assay is implemented prospectively to inform patient enrollment in genomically matched clinical trials at Memorial Sloan Kettering Cancer Center (MSKCC). Sequencing results of tumor...

Alternative Titles

Full title

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Authors, Artists and Contributors

Author / Creator

Zehir, Ahmet
Benayed, Ryma
Shah, Ronak H
Syed, Aijazuddin
Middha, Sumit
Kim, Hyunjae R
Srinivasan, Preethi
Gao, Jianjiong
Chakravarty, Debyani
Devlin, Sean M
Hellmann, Matthew D
Barron, David A
Schram, Alison M
Hameed, Meera
Dogan, Snjezana
Ross, Dara S
Hechtman, Jaclyn F
DeLair, Deborah F
Yao, JinJuan
Mandelker, Diana L
Cheng, Donavan T
Chandramohan, Raghu
Mohanty, Abhinita S
Ptashkin, Ryan N
Jayakumaran, Gowtham
Prasad, Meera
Syed, Mustafa H
Rema, Anoop Balakrishnan
Liu, Zhen Y
Nafa, Khedoudja
Borsu, Laetitia
Sadowska, Justyna
Casanova, Jacklyn
Bacares, Ruben
Kiecka, Iwona J
Razumova, Anna
Son, Julie B
Stewart, Lisa
Baldi, Tessara
Mullaney, Kerry A
Al-Ahmadie, Hikmat
Vakiani, Efsevia
Abeshouse, Adam A
Penson, Alexander V
Jonsson, Philip
Camacho, Niedzica
Chang, Matthew T
Won, Helen H
Gross, Benjamin E
Kundra, Ritika
Heins, Zachary J
Chen, Hsiao-Wei
Phillips, Sarah
Zhang, Hongxin
Wang, Jiaojiao
Ochoa, Angelica
Wills, Jonathan
Eubank, Michael
Thomas, Stacy B
Gardos, Stuart M
Reales, Dalicia N
Galle, Jesse
Durany, Robert
Cambria, Roy
Abida, Wassim
Cercek, Andrea
Feldman, Darren R
Gounder, Mrinal M
Hakimi, A Ari
Harding, James J
Iyer, Gopa
Janjigian, Yelena Y
Jordan, Emmet J
Kelly, Ciara M
Lowery, Maeve A
Morris, Luc G T
Omuro, Antonio M
Raj, Nitya
Razavi, Pedram
Shoushtari, Alexander N
Shukla, Neerav
Soumerai, Tara E
Varghese, Anna M
Yaeger, Rona
Coleman, Jonathan
Bochner, Bernard
Riely, Gregory J
Saltz, Leonard B
Scher, Howard I
Sabbatini, Paul J
Robson, Mark E
Klimstra, David S
Taylor, Barry S
Baselga, Jose
Schultz, Nikolaus
Hyman, David M
Arcila, Maria E
Solit, David B
Ladanyi, Marc
Berger, Michael F

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5461196

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5461196

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.4333

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