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Normalizing single-cell RNA sequencing data: challenges and opportunities

Normalizing single-cell RNA sequencing data: challenges and opportunities

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5549838

Normalizing single-cell RNA sequencing data: challenges and opportunities

About this item

Full title

Normalizing single-cell RNA sequencing data: challenges and opportunities

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2017-06, Vol.14 (6), p.565-571

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

This Perspective examines single-cell RNA-seq data challenges and the need for normalization methods designed specifically for single-cell data in order to remove technical biases.
Single-cell transcriptomics is becoming an important component of the molecular biologist's toolkit. A critical step when analyzing data generated using this technolo...

Alternative Titles

Full title

Normalizing single-cell RNA sequencing data: challenges and opportunities

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5549838

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5549838

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/nmeth.4292

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