Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex
Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex
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Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
The mammalian brain contains diverse neuronal types, yet we lack single-cell epigenomic assays that are able to identify and characterize them. DNA methylation is a stable epigenetic mark that distinguishes cell types and marks regulatory elements. We generated >6000 methylomes from single neuronal nuclei and used them to identify 16 mouse and 21 h...
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Full title
Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5570439
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5570439
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aan3351
