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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5608080

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Human glioblastomas harbour a subpopulation of glioblastoma stem cells that drive tumorigenesis. However, the origin of intratumoural functional heterogeneity between glioblastoma cells remains poorly understood. Here we study the clonal evolution of barcoded glioblastoma cells in an unbiased way following serial xenotransplantation to define their...

Alternative Titles

Full title

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5608080

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5608080

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature23666

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