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Modeling the process of human tumorigenesis
Author / Creator:Balani, Sneha ; Nguyen, Long V. ; Eaves, Connie J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-05, Vol.8 (1), p.15422-10, Article 15422
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Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
Author / Creator:Fares, Iman ; Chagraoui, Jalila ; Gareau, Yves ; Gingras, Stéphane ; Ruel, Réjean ; Mayotte, Nadine ; Csaszar, Elizabeth ; Knapp, David J. H. F. ; Miller, Paul ; Ngom, Mor ; Imren, Suzan ; Roy, Denis-Claude ; Watts, Kori L. ; Kiem, Hans-Peter ; Herrington, Robert ; Iscove, Norman N. ; Humphries, R. Keith ; Eaves, Connie J. ; Cohen, Sandra ; Marinier, Anne ; Zandstra, Peter W. ; Sauvageau, Guy
Publisher:Washington: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-09, Vol.345 (6203), p.1509-1512
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The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells
Author / Creator:Copley, Michael R. ; Babovic, Sonja ; Benz, Claudia ; Knapp, David J. H. F. ; Beer, Philip A. ; Kent, David G. ; Wohrer, Stefan ; Treloar, David Q. ; Day, Christopher ; Rowe, Keegan ; Mader, Heidi ; Kuchenbauer, Florian ; Humphries, R. Keith ; Eaves, Connie J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2013-08, Vol.15 (8), p.916-925
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Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells
Author / Creator:Nguyen, Long V. ; Pellacani, Davide ; Lefort, Sylvain ; Kannan, Nagarajan ; Osako, Tomo ; Makarem, Maisam ; Cox, Claire L. ; Kennedy, William ; Beer, Philip ; Carles, Annaick ; Moksa, Michelle ; Bilenky, Misha ; Balani, Sneha ; Babovic, Sonja ; Sun, Ivan ; Rosin, Miriam ; Aparicio, Samuel ; Hirst, Martin ; Eaves, Connie J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-12, Vol.528 (7581), p.267-271
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Modification of BRCA1-associated breast cancer risk by HMMR overexpression
Author / Creator:Mateo, Francesca ; He, Zhengcheng ; Mei, Lin ; de Garibay, Gorka Ruiz ; Herranz, Carmen ; García, Nadia ; Lorentzian, Amanda ; Baiges, Alexandra ; Blommaert, Eline ; Gómez, Antonio ; Mirallas, Oriol ; Garrido-Utrilla, Anna ; Palomero, Luis ; Espín, Roderic ; Extremera, Ana I. ; Soler-Monsó, M. Teresa ; Petit, Anna ; Li, Rong ; Brunet, Joan ; Chen, Ke ; Tan, Susanna ; Eaves, Connie J. ; McCloskey, Curtis ; Hakem, Razq ; Khokha, Rama ; Lange, Philipp F. ; Lázaro, Conxi ; Maxwell, Christopher A. ; Pujana, Miquel Angel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.1895-16, Article 1895
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High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays
Author / Creator:Lecault, Véronique ; VanInsberghe, Michael ; Sekulovic, Sanja ; Knapp, David J H F ; Wohrer, Stefan ; Bowden, William ; Viel, Francis ; McLaughlin, Thomas ; Jarandehei, Asefeh ; Miller, Michelle ; Falconnet, Didier ; White, Adam K ; Kent, David G ; Copley, Michael R ; Taghipour, Fariborz ; Eaves, Connie J ; Humphries, R Keith ; Piret, James M ; Hansen, Carl L
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2011-07, Vol.8 (7), p.581-586
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Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets
Author / Creator:Kannan, Nagarajan ; Nguyen, Long V. ; Makarem, Maisam ; Dong, Yifei ; Shih, Kingsley ; Eirew, Peter ; Raouf, Afshin ; Emerman, Joanne T. ; Eaves, Connie J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (21), p.7789-7794
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ArticlesPeer ReviewedFull Text
Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation
Author / Creator:He, Zhengcheng ; Ghorayeb, Ryan ; Tan, Susanna ; Chen, Ke ; Lorentzian, Amanda C. ; Bottyan, Jack ; Aalam, Syed Mohammed Musheer ; Pujana, Miguel Angel ; Lange, Philipp F. ; Kannan, Nagarajan ; Eaves, Connie J. ; Maxwell, Christopher A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.2200-17, Article 2200
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Initiation of human mammary cell tumorigenesis by mutant KRAS requires YAP inactivation
Author / Creator:Lefort, Sylvain ; Tan, Susanna ; Balani, Sneha ; Rafn, Bo ; Pellacani, Davide ; Hirst, Martin ; Sorensen, Poul H. ; Eaves, Connie J.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-02, Vol.39 (9), p.1957-1968
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ArticlesPeer ReviewedFull Text
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
Author / Creator:Bowie, Michelle B ; Kent, David G ; Dykstra, Brad ; McKnight, Kristen D ; McCaffrey, Lindsay ; Hoodless, Pamela A ; Eaves, Connie J
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (14), p.5878-5882
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ArticlesPeer ReviewedFull Text
Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells
Author / Creator:Makarem, Maisam ; Kannan, Nagarajan ; Nguyen, Long V ; Knapp, David J H F ; Balani, Sneha ; Prater, Michael D ; Stingl, John ; Raouf, Afshin ; Nemirovsky, Oksana ; Eirew, Peter ; Eaves, Connie J
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2013-08, Vol.11 (8), p.e1001630-e1001630
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ArticlesPeer ReviewedFull Text
Human milk protein production in xenografts of genetically engineered bovine mammary epithelial stem cells
Author / Creator:Martignani, Eugenio ; Eirew, Peter ; Accornero, Paolo ; Eaves, Connie J ; Baratta, Mario
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-10, Vol.5 (10), p.e13372-e13372
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ArticlesPeer ReviewedFull Text
Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth
Author / Creator:Zhou, Haixia ; Ge, Yue ; Sun, Lili ; Ma, Wenjuan ; Wu, Jie ; Zhang, Xiuyan ; Hu, Xiaohui ; Eaves, Connie J ; Wu, Depei ; Zhao, Yun
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e86195-e86195
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Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia
Author / Creator:Kusakabe, Manabu ; Sun, Ann Chong ; Tyshchenko, Kateryna ; Wong, Rachel ; Nanda, Aastha ; Shanna, Claire ; Gusscott, Samuel ; Chavez, Elizabeth A. ; Lorzadeh, Alireza ; Zhu, Alice ; Hill, Ainsleigh ; Hung, Stacy ; Brown, Scott ; Babaian, Artem ; Wang, Xuehai ; Holt, Robert A. ; Steidl, Christian ; Karsan, Aly ; Humphries, R. Keith ; Eaves, Connie J. ; Hirst, Martin ; Weng, Andrew P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.2913-15, Article 2913
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Dependence of human cell survival and proliferation on the CASP3 prodomain
Author / Creator:Eskandari, Ebrahim ; Negri, Gian Luca ; Tan, Susanna ; MacAldaz, Margarita E. ; Ding, Shengsen ; Long, Justin ; Nielsen, Karina ; Spencer, Sandra E. ; Morin, Gregg B. ; Eaves, Connie J.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death discovery, 2024-02, Vol.10 (1), p.63-63, Article 63
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ArticlesPeer ReviewedFull Text
Cancer stem cells: an evolving concept
Author / Creator:Nguyen, Long V. ; Vanner, Robert ; Dirks, Peter ; Eaves, Connie J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2012-02, Vol.12 (2), p.133-143
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Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability
Author / Creator:Law, Jennifer H ; Li, Yvonne ; To, Karen ; Wang, Michelle ; Astanehe, Arezoo ; Lambie, Karen ; Dhillon, Jaspreet ; Jones, Steven J M ; Gleave, Martin E ; Eaves, Connie J ; Dunn, Sandra E
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-09, Vol.5 (9), p.e12661
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Control of the hematopoietic stem cell state
Author / Creator:Knapp, David JHF ; Eaves, Connie J
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2014-01, Vol.24 (1), p.3-4
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Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene
Author / Creator:Lai, Courteney K ; Moon, Yeonsook ; Kuchenbauer, Florian ; Starzcynowski, Daniel T ; Argiropoulos, Bob ; Yung, Eric ; Beer, Philip ; Schwarzer, Adrian ; Sharma, Amit ; Park, Gyeongsin ; Leung, Malina ; Lin, Grace ; Vollett, Sarah ; Fung, Stephen ; Eaves, Connie J ; Karsan, Aly ; Weng, Andrew P ; Humphries, R Keith ; Heuser, Michael
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-11, Vol.9 (11), p.e112671-e112671
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ArticlesPeer ReviewedFull Text
Epithelial progenitors in the normal human mammary gland
Author / Creator:Stingl, John ; Raouf, Afshin ; Emerman, Joanne T ; Eaves, Connie J
Publisher:United States: Springer Nature B.V
Journal title:Journal of mammary gland biology and neoplasia, 2005-01, Vol.10 (1), p.49-59
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Modeling the process of human tumorigenesis

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Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

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The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

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Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells

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Modification of BRCA1-associated breast cancer risk by HMMR overexpression

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High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays

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Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets

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Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation

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Initiation of human mammary cell tumorigenesis by mutant KRAS requires YAP inactivation

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Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties

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Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells

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Human milk protein production in xenografts of genetically engineered bovine mammary epithelial stem cells

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Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth

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Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia

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Dependence of human cell survival and proliferation on the CASP3 prodomain

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Cancer stem cells: an evolving concept

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Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability

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Control of the hematopoietic stem cell state

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Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene

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Epithelial progenitors in the normal human mammary gland

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