Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
About this item
Full title
Author / Creator
Stone, Richard M , Mandrekar, Sumithra J , Sanford, Ben L , Laumann, Kristina , Geyer, Susan , Bloomfield, Clara D , Thiede, Christian , Prior, Thomas W , Döhner, Konstanze , Marcucci, Guido , Lo-Coco, Francesco , Klisovic, Rebecca B , Wei, Andrew , Sierra, Jorge , Sanz, Miguel A , Brandwein, Joseph M , de Witte, Theo , Niederwieser, Dietger , Appelbaum, Frederick R , Medeiros, Bruno C , Tallman, Martin S , Krauter, Jürgen , Schlenk, Richard F , Ganser, Arnold , Serve, Hubert , Ehninger, Gerhard , Amadori, Sergio , Larson, Richard A and Döhner, Hartmut
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Midostaurin, an oral multitargeted kinase inhibitor, is active in patients with a
FLT3
mutation. Among patients with acute myeloid leukemia and this mutation, the addition of midostaurin to standard chemotherapy appeared to improve long-term outcomes.
Alternative Titles
Full title
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
Authors, Artists and Contributors
Author / Creator
Mandrekar, Sumithra J
Sanford, Ben L
Laumann, Kristina
Geyer, Susan
Bloomfield, Clara D
Thiede, Christian
Prior, Thomas W
Döhner, Konstanze
Marcucci, Guido
Lo-Coco, Francesco
Klisovic, Rebecca B
Wei, Andrew
Sierra, Jorge
Sanz, Miguel A
Brandwein, Joseph M
de Witte, Theo
Niederwieser, Dietger
Appelbaum, Frederick R
Medeiros, Bruno C
Tallman, Martin S
Krauter, Jürgen
Schlenk, Richard F
Ganser, Arnold
Serve, Hubert
Ehninger, Gerhard
Amadori, Sergio
Larson, Richard A
Döhner, Hartmut
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5754190
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5754190
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1614359