Capicua controls Toll/IL-1 signaling targets independently of RTK regulation
Capicua controls Toll/IL-1 signaling targets independently of RTK regulation
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The HMG-box protein Capicua (Cic) is a conserved transcriptional repressor that functions downstream of receptor tyrosine kinase (RTK) signaling pathways in a relatively simple switch: In the absence of signaling, Cic represses RTK-responsive genes by binding to nearly invariant sites in DNA, whereas activation of RTK signaling down-regulates Cic a...
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Full title
Capicua controls Toll/IL-1 signaling targets independently of RTK regulation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5828586
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5828586
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1713930115