LSD1 activates a lethal prostate cancer gene network independently of its demethylase function
LSD1 activates a lethal prostate cancer gene network independently of its demethylase function
About this item
Full title
Author / Creator
Sehrawat, Archana , Gao, Lina , Wang, Yuliang , Bankhead, Armand , McWeeney, Shannon K. , King, Carly J. , Schwartzman, Jacob , Urrutia, Joshua , Bisson, William H. , Coleman, Daniel J. , Joshi, Sunil K. , Kim, Dae-Hwan , Sampson, David A. , Weinmann, Sheila , Kallakury, Bhaskar V. S. , Berry, Deborah L. , Haque, Reina , Van Den Eeden, Stephen K. , Sharma, Sunil , Bearss, Jared , Beer, Tomasz M. , Thomas, George V. , Heiser, Laura M. and Alumkal, Joshi J.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Medical castration that interferes with androgen receptor (AR) function is the principal treatment for advanced prostate cancer. However, clinical progression is universal, and tumors with AR-independent resistance mechanisms appear to be increasing in frequency. Consequently, there is an urgent need to develop new treatments targeting molecular pa...
Alternative Titles
Full title
LSD1 activates a lethal prostate cancer gene network independently of its demethylase function
Authors, Artists and Contributors
Author / Creator
Gao, Lina
Wang, Yuliang
Bankhead, Armand
McWeeney, Shannon K.
King, Carly J.
Schwartzman, Jacob
Urrutia, Joshua
Bisson, William H.
Coleman, Daniel J.
Joshi, Sunil K.
Kim, Dae-Hwan
Sampson, David A.
Weinmann, Sheila
Kallakury, Bhaskar V. S.
Berry, Deborah L.
Haque, Reina
Van Den Eeden, Stephen K.
Sharma, Sunil
Bearss, Jared
Beer, Tomasz M.
Thomas, George V.
Heiser, Laura M.
Alumkal, Joshi J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5939079
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5939079
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1719168115
