nNOS–CAPON interaction mediates amyloid‐β‐induced neurotoxicity, especially in the early stages
nNOS–CAPON interaction mediates amyloid‐β‐induced neurotoxicity, especially in the early stages
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Author / Creator
Zhang, Yu , Zhu, Zhu , Liang, Hai‐Ying , Zhang, Lei , Zhou, Qi‐Gang , Ni, Huan‐Yu , Luo, Chun‐Xia and Zhu, Dong‐Ya
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
Summary
In neurons, increased protein–protein interactions between neuronal nitric oxide synthase (nNOS) and its carboxy‐terminal PDZ ligand (CAPON) contribute to excitotoxicity and abnormal dendritic spine development, both of which are involved in the development of Alzheimer's disease. In models of Alzheimer's disease, increased nNOS–CAPON in...
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Full title
nNOS–CAPON interaction mediates amyloid‐β‐induced neurotoxicity, especially in the early stages
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5946066
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5946066
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12754
