Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR
Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
CD4
+
T regulatory cells (T
reg
) are central to immune homeostasis, their phenotypic heterogeneity reflecting the diverse environments and target cells that they regulate. To understand this heterogeneity, we combined single-cell RNA-seq, activation reporter and T cell receptor (TCR) analysis to profile thousands of T
reg
or conv...
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Full title
Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6069633
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6069633
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0051-0
