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A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143402

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

About this item

Full title

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2018-10, Vol.14 (10), p.964-971

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

RNAs directly regulate a vast array of cellular processes, emphasizing the need for robust approaches to fluorescently label and track RNAs in living cells. Here, we develop an RNA imaging platform using the cobalamin riboswitch as an RNA tag and a series of probes containing cobalamin as a fluorescence quencher. This highly modular ‘Riboglow’ plat...

Alternative Titles

Full title

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143402

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143402

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-018-0103-7

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