A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
RNAs directly regulate a vast array of cellular processes, emphasizing the need for robust approaches to fluorescently label and track RNAs in living cells. Here, we develop an RNA imaging platform using the cobalamin riboswitch as an RNA tag and a series of probes containing cobalamin as a fluorescence quencher. This highly modular ‘Riboglow’ plat...
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Full title
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143402
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6143402
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-018-0103-7