Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
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Author / Creator
TCGA Consortium , CAMCAP Study Group , The TCGA Consortium , Wedge, David C. , Gundem, Gunes , Mitchell, Thomas , Woodcock, Dan J. , Martincorena, Inigo , Ghori, Mohammed , Zamora, Jorge , Butler, Adam , Whitaker, Hayley , Kote-Jarai, Zsofia , Alexandrov, Ludmil B. , Van Loo, Peter , Massie, Charlie E. , Dentro, Stefan , Warren, Anne Y. , Verrill, Clare , Berney, Dan M. , Dennis, Nening , Merson, Sue , Hawkins, Steve , Howat, William , Lu, Yong-Jie , Lambert, Adam , Kay, Jonathan , Kremeyer, Barbara , Karaszi, Katalin , Luxton, Hayley , Camacho, Niedzica , Marsden, Luke , Edwards, Sandra , Matthews, Lucy , Bo, Valeria , Leongamornlert, Daniel , McLaren, Stuart , Ng, Anthony , Yu, Yongwei , Zhang, Hongwei , Dadaev, Tokhir , Thomas, Sarah , Easton, Douglas F. , Ahmed, Mahbubl , Bancroft, Elizabeth , Fisher, Cyril , Livni, Naomi , Nicol, David , Tavaré, Simon , Gill, Pelvender , Greenman, Christopher , Khoo, Vincent , Van As, Nicholas , Kumar, Pardeep , Ogden, Christopher , Cahill, Declan , Thompson, Alan , Mayer, Erik , Rowe, Edward , Dudderidge, Tim , Gnanapragasam, Vincent , Shah, Nimish C. , Raine, Keiran , Jones, David , Menzies, Andrew , Stebbings, Lucy , Teague, Jon , Hazell, Steven , Corbishley, Cathy , de Bono, Johann , Attard, Gerhardt , Isaacs, William , Visakorpi, Tapio , Fraser, Michael , Boutros, Paul C. , Bristow, Robert G. , Workman, Paul , Sander, Chris , Hamdy, Freddie C. , Futreal, Andrew , McDermott, Ultan , Al-Lazikani, Bissan , Lynch, Andrew G. , Bova, G. Steven , Foster, Christopher S. , Brewer, Daniel S. , Neal, David E. , Cooper, Colin S. and Eeles, Rosalind A.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Prostate cancer represents a substantial clinical challenge because it is difficult to predict outcome and advanced disease is often fatal. We sequenced the whole genomes of 112 primary and metastatic prostate cancer samples. From joint analysis of these cancers with those from previous studies (930 cancers in total), we found evidence for 22 previ...
Alternative Titles
Full title
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
Authors, Artists and Contributors
Author / Creator
CAMCAP Study Group
The TCGA Consortium
Wedge, David C.
Gundem, Gunes
Mitchell, Thomas
Woodcock, Dan J.
Martincorena, Inigo
Ghori, Mohammed
Zamora, Jorge
Butler, Adam
Whitaker, Hayley
Kote-Jarai, Zsofia
Alexandrov, Ludmil B.
Van Loo, Peter
Massie, Charlie E.
Dentro, Stefan
Warren, Anne Y.
Verrill, Clare
Berney, Dan M.
Dennis, Nening
Merson, Sue
Hawkins, Steve
Howat, William
Lu, Yong-Jie
Lambert, Adam
Kay, Jonathan
Kremeyer, Barbara
Karaszi, Katalin
Luxton, Hayley
Camacho, Niedzica
Marsden, Luke
Edwards, Sandra
Matthews, Lucy
Bo, Valeria
Leongamornlert, Daniel
McLaren, Stuart
Ng, Anthony
Yu, Yongwei
Zhang, Hongwei
Dadaev, Tokhir
Thomas, Sarah
Easton, Douglas F.
Ahmed, Mahbubl
Bancroft, Elizabeth
Fisher, Cyril
Livni, Naomi
Nicol, David
Tavaré, Simon
Gill, Pelvender
Greenman, Christopher
Khoo, Vincent
Van As, Nicholas
Kumar, Pardeep
Ogden, Christopher
Cahill, Declan
Thompson, Alan
Mayer, Erik
Rowe, Edward
Dudderidge, Tim
Gnanapragasam, Vincent
Shah, Nimish C.
Raine, Keiran
Jones, David
Menzies, Andrew
Stebbings, Lucy
Teague, Jon
Hazell, Steven
Corbishley, Cathy
de Bono, Johann
Attard, Gerhardt
Isaacs, William
Visakorpi, Tapio
Fraser, Michael
Boutros, Paul C.
Bristow, Robert G.
Workman, Paul
Sander, Chris
Hamdy, Freddie C.
Futreal, Andrew
McDermott, Ultan
Al-Lazikani, Bissan
Lynch, Andrew G.
Bova, G. Steven
Foster, Christopher S.
Brewer, Daniel S.
Neal, David E.
Cooper, Colin S.
Eeles, Rosalind A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6372064
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6372064
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-018-0086-z
