Mitochondrial double-stranded RNA triggers antiviral signalling in humans
Mitochondrial double-stranded RNA triggers antiviral signalling in humans
About this item
Full title
Author / Creator
Dhir, Ashish , Dhir, Somdutta , Borowski, Lukasz S. , Jimenez, Laura , Teitell, Michael , Rötig, Agnès , Crow, Yanick J. , Rice, Gillian I. , Duffy, Darragh , Tamby, Christelle , Nojima, Takayuki , Munnich, Arnold , Schiff, Manuel , de Almeida, Claudia Ribeiro , Rehwinkel, Jan , Dziembowski, Andrzej , Szczesny, Roman J. and Proudfoot, Nicholas J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mitochondria are descendants of endosymbiotic bacteria and retain essential prokaryotic features such as a compact circular genome. Consequently, in mammals, mitochondrial DNA is subjected to bidirectional transcription that generates overlapping transcripts, which are capable of forming long double-stranded RNA structures
1
,
2
. Howev...
Alternative Titles
Full title
Mitochondrial double-stranded RNA triggers antiviral signalling in humans
Authors, Artists and Contributors
Author / Creator
Dhir, Somdutta
Borowski, Lukasz S.
Jimenez, Laura
Teitell, Michael
Rötig, Agnès
Crow, Yanick J.
Rice, Gillian I.
Duffy, Darragh
Tamby, Christelle
Nojima, Takayuki
Munnich, Arnold
Schiff, Manuel
de Almeida, Claudia Ribeiro
Rehwinkel, Jan
Dziembowski, Andrzej
Szczesny, Roman J.
Proudfoot, Nicholas J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6570621
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6570621
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0363-0
