Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of p...
Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3
About this item
Full title
Author / Creator
German Consortium for Frontotemporal Lobar Degeneration , Bavarian Brain Banking Alliance , Nihei, Yoshihiro , Mori, Kohji , Werner, Georg , Arzberger, Thomas , Zhou, Qihui , Khosravi, Barham , Japtok, Julia , Hermann, Andreas , Sommacal, Andreas , Weber, Markus , Kamp, Frits , Nuscher, Brigitte , Edbauer, Dieter and Haass, Christian
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Repeat expansion in
C9orf72
causes amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Expanded sense and antisense repeat RNA transcripts in
C9orf72
are translated into five dipeptide-repeat proteins (DPRs) in an AUG-independent manner. We previously identified the heterogeneous ribonucleoprotein (hnRNP) A3 as an inter...
Alternative Titles
Full title
Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3
Authors, Artists and Contributors
Author / Creator
Bavarian Brain Banking Alliance
Nihei, Yoshihiro
Mori, Kohji
Werner, Georg
Arzberger, Thomas
Zhou, Qihui
Khosravi, Barham
Japtok, Julia
Hermann, Andreas
Sommacal, Andreas
Weber, Markus
Kamp, Frits
Nuscher, Brigitte
Edbauer, Dieter
Haass, Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6942035
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6942035
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-019-02082-0
