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KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3...

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7212036

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

About this item

Full title

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2020-04, Vol.22 (4), p.380-388

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The importance of germline-inherited post-translational histone modifications on priming early mammalian development is just emerging
1

4
. Histone H3 lysine 9 (H3K9) trimethylation is associated with heterochromatin and gene repression during cell-fate change
5
, whereas histone H3 lysine 4 (H3K4) trimethylation marks active ge...

Alternative Titles

Full title

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7212036

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7212036

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-020-0494-z

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